Volume I of The Complete Sherlock Holmes starts with Holmes's first appearance. A Study in Scarlet, a chilling murder novel complete with bloodstained walls and cryptic clues, followed by the baffling The Sign of Four, which introduces Holmes's cocain problem and Watson's future wife. The story collections The Adventures of Sherlock Holmes and The Memoirs of Sherlock Holmes feature such renowned tales as "A Scandal in Bohemia," "The Red-Headed League," and "The Musgrave Ritual. Tired of writing stories about Holmes, his creator, Sir Arthur Conan Doyle, killed him off at the end of "The Final Problem," the last tale in The Memoirs. But the public outcry was so great that eight years later he published the masterful The Hound of the Baskervilles, which supposedly takes place before Holmes's death.